Semaglutide is part of the glucagon-like peptide-1 (GLP-1) receptor targeting family of peptide drugs which are mainly used to treat diabetes but are difficult and expensive to make.
Biochemistry
Mar 12, 2024
0
68
Protein glycosylation is one of the most important post-translational modifications that can be exploited to improve various aspects of therapeutic proteins and industrial enzymes. Different types of glycosylation have a ...
Molecular & Computational biology
Sep 8, 2023
0
1
Many proteins in nature exist as glycoproteins, which consist of protein (polypeptide chain) and glycan (sugar chain). The protein structure is determined on the basis of its genetic blueprint, but the information on glycans ...
Biochemistry
Jul 13, 2022
0
15
Glycosylation is a common post-translational modification (PTM) of proteins and plays a crucial role in many biological processes. Many disease biomarkers are glycosylated proteins.
Biotechnology
Apr 8, 2022
0
8
New tools and methods have been described by WEHI researchers to study an unusual protein modification and gain fresh insights into its roles in human health and disease.
Cell & Microbiology
Feb 4, 2021
0
43
Scientists at EMBL Rome unveil the mechanism behind the most studied epigenetic modification.
Biotechnology
Jun 11, 2020
0
110
When Lorna De Leoz invited laboratories to participate in her glycomics study, she hoped for 20 responses. Instead, she was deluged by emails from around the world.
Molecular & Computational biology
Jan 2, 2020
0
55
Cells of all living organisms are covered by a dense layer of highly complex carbohydrates. These carbohydrates, which are also known as glycans, are essential mediators of a wide range of biological and disease processes. ...
Biochemistry
Apr 1, 2019
0
21
Engineering cellular biology, minus the actual cell, is a growing area of interest in biotechnology and synthetic biology. It's known as cell-free protein synthesis, or CFPS, and it has potential to provide sustainable ways ...
Biochemistry
Jul 12, 2018
0
365
Differences in production methods for therapeutic antibodies can lead to variations in their structure, depending on the recombinant procedure selected. The distinctions, which are based on a number of glycosylations, even ...
Biochemistry
Jul 10, 2018
0
10
