Therapeutic antibodies are increasingly being used in the clinic for the treatment of diseases. Yet, oral to gut targeting of antibodies remains a challenge due to their inability to survive digestion and reach gastrointestinal ...
Cell & Microbiology
Apr 1, 2019
0
115
A research team led by Dr. Xiang David Li from the Department of Chemistry at The University of Hong Kong (HKU), in collaboration with scientists from Tsinghua University in China, the Rockefeller University, and the University ...
Biochemistry
Nov 7, 2018
0
68
The search for new medicinal molecules with predetermined properties is a complex, expensive and time-consuming process, especially in oncology. Modern science allows us to accelerate this search through the use of computer ...
Biochemistry
Aug 14, 2018
0
5
In a milestone achievement for better understanding the development and function of the human placenta, scientists have derived and grown trophoblast stem cells for the first time.
Cell & Microbiology
Jan 25, 2018
0
30
Doctors have long treated heart attacks, improved asthma symptoms, and cured impotence by increasing levels of a single molecule in the body: nitric oxide.
Biochemistry
Jan 18, 2018
0
9
Immune cells called "killer cells" target bacteria invading the body's cells, but how do they do this so effectively? Bacteria can quickly evolve resistance against antibiotics, yet it seems they have not so readily been ...
Cell & Microbiology
Nov 8, 2017
0
93
An enzyme that helps break down cholesterol may also be a therapeutic target to stave off neurologic diseases, including Alzheimer's and a rare genetic disorder, according to a new study published in the Journal of Biological ...
Biochemistry
Mar 1, 2017
0
12
Prostate cancer, Alzheimer's, Parkinson's...these three diseases are associated with proteins that share a common feature, namely disordered regions that have no apparent rigid three-dimensional structure. In spite of the ...
Biochemistry
Aug 16, 2016
0
9
Scientists have described an improved, cost-efficient method to isolate membrane proteins, a class of proteins that are the targets of more than 60 percent of approved therapeutic drugs.
Cell & Microbiology
Jul 25, 2016
0
5
Knowledge of the minute details of the proteins that are linked to diseases is crucial if we are to discover therapeutic targets and thus pave the way for possible treatments. Such knowledge gains even more relevance when ...
Biochemistry
Jun 10, 2016
0
14
