Vanderbilt University researchers have discovered how a protein pump distinguishes between chemicals that it will expel from a cell and inhibitors that block its action.
Biochemistry
May 31, 2019
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15
A machine-learning model from MIT researchers computationally breaks down how segments of amino acid chains determine a protein's function, which could help researchers design and test new proteins for drug development or ...
Biochemistry
Mar 25, 2019
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45
It is now possible to create complex, custom-designed transmembrane proteins from scratch, scientists report this week. The advance, led by molecular engineers at the University of Washington Institute for Protein Design, ...
Biochemistry
Mar 1, 2018
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479
Ever heard of polarons? They are a kind of quasi-particle resulting from electrons self-trapping in a vibrating crystal lattice. Polarons can be harnessed to transport energy under certain conditions related to the relative ...
General Physics
Sep 13, 2017
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2
Osaka University researchers use X-ray crystallography and electron microscopy to resolve the assembly of the export gate apparatus in Salmonella. The new details of this nanomachine are expected to clarify how bacteria infect ...
Bio & Medicine
Aug 9, 2017
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8
New research at the University of Arkansas shows that arginine – one of 20 common amino acids – does not change its positive charge when inserted into the lipid environment of the cell membrane.
Biochemistry
Nov 18, 2016
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4
Many bacterial species use spiral propellers (flagella) attached to motors to move through a liquid environment. An interaction between the rotor and stator components of the motor generates the rotational force required ...
Cell & Microbiology
Sep 7, 2016
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5
It sounds like science fiction to suggest that every cell in the human body is occupied by a tiny genome-equipped organelle, with which we exist in symbiosis. But in actuality, eukaryotic life is dependent on mitochondria, ...
Researchers reveal how a protein linked to Meckel syndrome (MKS) and other human diseases regulates the membrane composition of cilia, finger-like projections on the surface of cells that communicate signals. The study appears ...
Cell & Microbiology
Apr 13, 2015
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5
A key factor in the biosynthesis and stable expression of multi-pass transmembrane proteins was discovered, and its loss is thought to cause retinal degeneration. The factor works especially for multi-pass membrane proteins, ...
Cell & Microbiology
Mar 2, 2015
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