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Biochemistry news
Machine learning model uncovers new drug design opportunities
Pathogens are nothing if not adaptable, and their ability to protect themselves against antibiotics increasingly poses a public health concern. A research team led by Los Alamos National Laboratory has used machine learning, ...
Biochemistry
13 hours ago
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Finding the chink in coronavirus's armor—experiment reveals how the main protease of SARS-CoV-2 protects itself
The COVID-19 pandemic resulted in millions of deaths. Despite an unparalleled collaborative research effort that led to effective vaccines and therapies being produced in record-breaking time, a complete understanding of ...
Biochemistry
17 hours ago
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Researchers precisely characterize styrene oxide isomerase, which could help yield 'green' chemicals and drug precursors
Researchers at the Paul Scherrer Institute PSI have—for the first time—precisely characterized the enzyme styrene oxide isomerase, which can be used to produce valuable chemicals and drug precursors in an environmentally ...
Biochemistry
23 hours ago
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Researchers find new approach for antibiotic development
The opportunistic bacterial pathogen Pseudomonas aeruginosa is dangerous due to its resistance to multiple antibiotics. A research team from Heinrich Heine University Düsseldorf (HHU) and Jülich Research Center (Forschungszentrum ...
Biochemistry
May 13, 2024
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Chemists shows hemoprotein catalysis is way more complicated than we thought
Sometimes, serendipity—or just plain luck—still plays a pivotal role in scientific discovery. Recently, a team of chemists was experimenting with using a biocatalytic process to trigger a cyclopropanation reaction, which ...
Biochemistry
May 10, 2024
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Evolutionary algorithm generates tailored 'molecular fingerprints'
A team led by Prof Frank Glorius from the Institute of Organic Chemistry at the University of Münster has developed an evolutionary algorithm that identifies the structures in a molecule that are particularly relevant for ...
Biochemistry
May 10, 2024
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86
Shaping up how red blood cell deformability is assessed—researchers develop new approach
Red blood cells (RBCs) transport oxygen throughout the body and are able to pass through a complex of narrow capillaries due to their ability to deform. "The deformability of RBCs is an important indicator of their health ...
Biochemistry
May 8, 2024
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7
A multi-stream network for retrosynthesis prediction
Retrosynthesis aims to predict a set of reactants for producing given molecules, which plays a significant part in the biochemistry field, such as molecular pathway design and drug discovery. Most existing methods only benefit ...
Biochemistry
May 8, 2024
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Chemists produce new-to-nature enzyme containing boron
Boronic acid has been used in organic chemistry for decades, even though it is not present in any organism. "It gives rise to different chemical reactions than those we find in nature," explains Gerard Roelfes, Professor ...
Biochemistry
May 8, 2024
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453
Getting to know the enzymes behind cell communication—and tumor growth
In the human body, molecules known as kinases propagate signals within and between cells, relaying signals that allow cells to respond to changes in the environment. However, there are hundreds of different kinases in the ...
Biochemistry
May 8, 2024
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130
New research confirms that Beethoven had lead poisoning—but it didn't kill him
To this day, no one knows for certain what caused the liver and kidney disease that led to Ludwig van Beethoven's untimely death. However, a new letter to the editor in the journal Clinical Chemistry rules out one popular ...
Biochemistry
May 7, 2024
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Researchers develop bioinspired Bouligand structure for enhanced mechanical properties
Bouligand structures, found in natural materials like fish scales, lobster peritoneum and bones, are known for providing exceptional mechanical properties to biomaterials. While progress has been made in creating bioinspired ...
Biochemistry
May 7, 2024
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12
Geologists, biologists unearth the atomic fingerprints of cancer
Scientists at the University of Colorado Boulder and Princeton University have, for the first time, employed a tool often used in geology to detect the atomic fingerprints of cancer.
Biochemistry
May 6, 2024
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183
Simulated chemistry: New AI platform designs tomorrow's cancer drugs
Scientists at UC San Diego have developed a machine learning algorithm to simulate the time-consuming chemistry involved in the earliest phases of drug discovery, which could significantly streamline the process and open ...
Biochemistry
May 6, 2024
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Synthetic chemistry approach yields new compounds with potential biomedical applications
Researchers at Rice University have successfully synthesized a group of natural compounds known as fusicoccanes. The molecules found in various living organisms exhibit diverse biological activities, including the ability ...
Biochemistry
May 6, 2024
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122
Scientists use high pressure NMR spectroscopy to study structure of dynamic proteins
A pressure of 3,000 bar is applied to the cold shock protein B of Bacillus subtilis in a small tube in the NMR spectroscopy laboratory at the University of Konstanz. This is roughly three times the water pressure at the deepest ...
Biochemistry
May 6, 2024
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Functionalized chitosan as a biobased flocculant for the treatment of complex wastewater
Researchers at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB have developed a biobased and functionalized flocculant to efficiently treat complex wastewaters. Furthermore, toxic phenols are removed ...
Biochemistry
May 3, 2024
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Scientists show how to treat burns with an environmentally friendly plant-based bandage
The Smart Materials research group, coordinated by Athanassia Athanassiou at the Istituto Italiano di Tecnologia (Italian Institute of Technology), has developed a biocompatible bandage made of plant-based materials that, ...
Biochemistry
May 3, 2024
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53
Novel chemical tool for understanding membrane remodeling in the cell
In a study published in Proceedings of the National Academy of Sciences, Umeå researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes ...
Biochemistry
May 3, 2024
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30
Centipedes used in traditional Chinese medicine offer leads for kidney treatment
A venomous, 8-inch centipede may be the stuff of nightmares, but it could save the life of those affected by kidney disease. Researchers report in the Journal of Natural Products that the many-legged critter—used in traditional ...
Biochemistry
May 2, 2024
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